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PD-L1 in Cancer Immunotherapy: Insights from Recent ResearchRecent advancements in cancer immunotherapy have underscored the critical role of programmed death-ligand 1 (PD-L1) in mediating immune evasion by tumors. This article delves into how PD-L1 expression influences T-cell mediated immune evasion in cancer, contributing to improved biomarker targeting for immunotherapy. By exploring the molecular mechanisms, clinical implications, and future directions of PD-L1 research, we aim to provide a comprehensive understanding of its significance in the evolving landscape of cancer treatment.Introduction to PD-L1PD-L1, a protein expressed on the surface of various cells, plays a pivotal role in …

The Role of CD25+FOXP3+CD45RA- Treg Cells in Cancer PrognosisIntroductionRegulatory T-cells (Treg cells) are a specialized subset of T-cells that play a pivotal role in maintaining immune homeostasis and tolerance. These cells are essential for preventing autoimmune diseases and controlling excessive immune responses. However, in the context of cancer, Treg cells have garnered significant attention due to their dual roles in promoting tumor angiogenesis and modulating antitumor immunity. This article delves into the prognostic significance of CD25+FOXP3+CD45RA- Treg cell infiltration in tumor specimens, highlighting their potential as biomarkers for cancer outcomes.Study SummaryIn a comprehe …