ARFGAP1 Antibody (PACO04717)
- SKU:
- PACO04717
- Product Type:
- Antibody
- Host Species:
- Rabbit
- Reactivity:
- Human, Mouse, Rat, Monkey
- Size:
- 50 µg
- Target:
- ARFGAP1
Frequently bought together:
Description
| Antibody Name: | ARFGAP1 Antibody |
| Antibody SKU: | PACO04717 |
| Size: | 50 µg |
| Target Name: | ARFGAP1 |
| Host Species: | Rabbit |
| Tested Applications: | WB, IHC, IF, ELISA |
| Recommended Dilutions: | WB:1:500-1:2000, IHC:1:100-1:300, IF:1:200-1:1000, ELISA:1:20000 |
| Species Reactivity: | Human,Mouse,Rat,Monkey |
| Immunogen: | Synthesized peptide derived from the Internal region of Human ARF GAP1. |
| Immunogen Species: | Homo sapiens (Human) |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage: | Store at -20°C or -80°C. Avoid repeated freeze. |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | ADP ribosylation factor 1 GTPase activating protein antibody; ADP ribosylation factor GTPase activating protein 1 antibody; ADP-ribosylation factor 1 GTPase-activating protein antibody; ADP-ribosylation factor GTPase-activating protein 1 antibody; ARF GAP 1 antibody; ARF1 directed GTPase activating protein antibody; ARF1 GAP antibody; ARF1-directed GTPase-activating protein antibody; ARF1GAP antibody; ARFG1_HUMAN antibody; Arfgap1 antibody; GAP protein antibody; HRIHFB2281 antibody |
| UniProt Code: | Q8N6T3 |
| Target Background Function: | GTPase-activating protein (GAP) for the ADP ribosylation factor 1 (ARF1). Involved in membrane trafficking and /or vesicle transport. Promotes hydrolysis of the ARF1-bound GTP and thus, is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles, a prerequisite for vesicle's fusion with target compartment. Probably regulates ARF1-mediated transport via its interaction with the KDELR proteins and TMED2. Overexpression induces the redistribution of the entire Golgi complex to the endoplasmic reticulum, as when ARF1 is deactivated. Its activity is stimulated by phosphoinosides and inhibited by phosphatidylcholine. |
| Subcellular Location: | Cytoplasm. Golgi apparatus |
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