UniProt Protein Function: | OASL: a protein of the 2'-5'-oligoadenylate synthetase family, but does not have 2'-5'-OAS activity. Binds double-stranded RNA and DNA. Interacts with the ligand binding domain of the thyroid receptor (TR). Does not require the presence of thyroid hormone for its interaction. Contains a ubiquitin-like domain that interacts with methyl CpG-binding protein 1. |
UniProt Protein Details: | Protein type:DNA-binding; Nucleolus Chromosomal Location of Human Ortholog: 12q24.31 Cellular Component: cytoplasm; cytosol; membrane; nucleolus; nucleoplasm Molecular Function:2'-5'-oligoadenylate synthetase activity; DNA binding; double-stranded RNA binding; RNA binding; thyroid hormone receptor binding Biological Process: negative regulation of viral genome replication; response to virus |
UniProt Code: | Q15646 |
NCBI GenInfo Identifier: | 6226835 |
NCBI Gene ID: | 8638 |
NCBI Accession: | Q15646.2 |
UniProt Secondary Accession: | Q15646,O75686, Q17R95, Q9Y6K6, Q9Y6K7, B2RAZ2, I1YDD2 |
UniProt Related Accession: | Q15646 |
Molecular Weight: | 59kDa |
NCBI Full Name: | 2'-5'-oligoadenylate synthase-like protein |
NCBI Synonym Full Names: | 2'-5'-oligoadenylate synthetase like |
NCBI Official Symbol: | OASLÂ Â |
NCBI Official Synonym Symbols: | OASLd; TRIP14; TRIP-14; p59OASL; p59 OASL; p59-OASLÂ Â |
NCBI Protein Information: | 2'-5'-oligoadenylate synthase-like protein |
UniProt Protein Name: | 2'-5'-oligoadenylate synthase-like protein |
UniProt Synonym Protein Names: | 2'-5'-OAS-related protein; 2'-5'-OAS-RP; 59 kDa 2'-5'-oligoadenylate synthase-like protein; Thyroid receptor-interacting protein 14; TR-interacting protein 14; TRIP-14; p59 OASL; p59OASL |
Protein Family: | 2'-5'-oligoadenylate synthase-like protein |
UniProt Gene Name: | OASLÂ Â |