Description
Description | This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms. |
Product name | Anti-B7-2 antibody (DM85) Rabbit mAb |
Synonyms | CD86, B7-2, B70, CD28LG2, LAB72, MGC34413 |
Type | Primary |
Quantity | 100 µL |
Shipping | Blue Ice |
Antigen | B7-2 |
Reactivity | Human |
Host | Rabbit |
Clonality | Monoclonal |
Clone | DM85 |
Isotype | Rabbit IgG |
Application | ELISA,Flow Cyt |
Immunogen substitute | Recombinant human B7-2 (Leu26-Pro247) (HDPT0034) produced by using human HEK293 cells |
Purification | Purified from cell culture supernatant by affinity chromatography |
Format | Liquid |
Storage | Store at -20°C for 12 months (Avoid repeated freezing and thawing) |
Usage | Research use only |
Buffer | 50% Glycerol; PBS, pH 7.4; 0.1% BSA |
Preservative | 0.1% Procline 300 |
Reconstitution | Reconstitute with deionized water |
Application Advice | ELISA 1/5000-10000;Flow Cyt 1/100 |
Gene ID | 942 |
Swiss-Prot | P42081 |
Molecular Weight | 37.7kDa |
Assay Genie Related SKUs | HDPT0034 |