Anti-B7-2 antibody (DM86) Rabbit mAb (HDAB0073)

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Description

Description	This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.
Product name	Anti-B7-2 antibody (DM86) Rabbit mAb
Synonyms	CD86, B7-2, B70, CD28LG2, LAB72, MGC34413
Type	Primary
Quantity	100 µL
Shipping	Blue Ice
Antigen	B7-2
Reactivity	Human
Host	Rabbit
Clonality	Monoclonal
Clone	DM86
Isotype	Rabbit IgG
Application	ELISA,Flow Cyt
Immunogen substitute	Recombinant human B7-2 (Leu26-Pro247) (HDPT0034) produced by using human HEK293 cells
Purification	Purified from cell culture supernatant by affinity chromatography
Format	Liquid
Storage	Store at -20°C for 12 months (Avoid repeated freezing and thawing)
Usage	Research use only
Buffer	50% Glycerol; PBS, pH 7.4; 0.1% BSA
Preservative	0.1% Procline 300
Reconstitution	Reconstitute with deionized water
Application Advice	ELISA 1/5000-10000;Flow Cyt 1/100
Gene ID	942
Swiss-Prot	P42081
Molecular Weight	37.7kDa
Assay Genie Related SKUs	HDPT0034