Anti-B7-2 antibody (DM86) Rabbit mAb (HDAB0073)

SKU:
HDAB0073
€630

Description

DescriptionThis gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.
Product nameAnti-B7-2 antibody (DM86) Rabbit mAb
SynonymsCD86, B7-2, B70, CD28LG2, LAB72, MGC34413
TypePrimary
Quantity100 µL
ShippingBlue Ice
AntigenB7-2
ReactivityHuman
HostRabbit
ClonalityMonoclonal
CloneDM86
IsotypeRabbit IgG
ApplicationELISA,Flow Cyt
Immunogen substituteRecombinant human B7-2 (Leu26-Pro247) (HDPT0034) produced by using human HEK293 cells
PurificationPurified from cell culture supernatant by affinity chromatography
FormatLiquid
StorageStore at -20°C for 12 months (Avoid repeated freezing and thawing)
UsageResearch use only
Buffer50% Glycerol; PBS, pH 7.4; 0.1% BSA
Preservative0.1% Procline 300
ReconstitutionReconstitute with deionized water
Application AdviceELISA 1/5000-10000;Flow Cyt  1/100
Gene ID942
Swiss-ProtP42081
Molecular Weight37.7kDa
Assay Genie Related SKUsHDPT0034
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