Description
Description | The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Product name | Anti-B7H3 antibody (DM53) Rabbit mAb |
Synonyms | B7-H3, CD276, B7 homolog 3, B7H3 |
Type | Primary |
Quantity | 100 µL |
Shipping | Blue Ice |
Antigen | B7H3 |
Reactivity | Human |
Host | Rabbit |
Clonality | Monoclonal |
Clone | DM53 |
Isotype | Rabbit IgG |
Application | ELISA,Flow Cyt |
Immunogen substitute | Recombinant human B7H3(Leu29-Pro245) (HDPT0012) produced by using human HEK293 cells |
Purification | Purified from cell culture supernatant by affinity chromatography |
Format | Liquid |
Storage | Store at -20°C for 12 months (Avoid repeated freezing and thawing) |
Usage | Research use only |
Buffer | 50% Glycerol; PBS, pH 7.4; 0.1% BSA |
Preservative | 0.1% Procline 300 |
Reconstitution | Reconstitute with deionized water |
Application Advice | ELISA 1/5000-10000;Flow Cyt 1/100 |
Gene ID | 80381 |
Swiss-Prot | Q5ZPR3 |
Molecular Weight | 57 kDa |
Assay Genie Related SKUs | HDPT0012 |