Anti-B7H3 antibody (DM53) Rabbit mAb (HDAB0043)

SKU:
HDAB0043
€630

Description

DescriptionThe protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Product nameAnti-B7H3 antibody (DM53) Rabbit mAb
SynonymsB7-H3, CD276, B7 homolog 3, B7H3
TypePrimary
Quantity100 µL
ShippingBlue Ice
AntigenB7H3
ReactivityHuman
HostRabbit
ClonalityMonoclonal
CloneDM53
IsotypeRabbit IgG
ApplicationELISA,Flow Cyt
Immunogen substituteRecombinant human  B7H3(Leu29-Pro245) (HDPT0012) produced by using human HEK293 cells
PurificationPurified from cell culture supernatant by affinity chromatography
FormatLiquid
StorageStore at -20°C for 12 months (Avoid repeated freezing and thawing)
UsageResearch use only
Buffer50% Glycerol; PBS, pH 7.4; 0.1% BSA
Preservative0.1% Procline 300
ReconstitutionReconstitute with deionized water
Application AdviceELISA 1/5000-10000;Flow Cyt  1/100
Gene ID80381
Swiss-ProtQ5ZPR3
Molecular Weight57 kDa
Assay Genie Related SKUsHDPT0012
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