Anti-BCMA bispecific antibody (DM4) (HDAB0001)
- SKU:
- HDAB0001
Frequently bought together:
Description
| Description | BiTE bispecific antibody is an Engineered fusion protein constructed from two single-chain variable fragments (scFvs) of different monoclonal antibodies. One of the scFvs will be constructed from an anti-CD3 monoclonal antibody, and the other scFv fragment which linked by a linker region will be made from an anti-Tumor cell specific monoclonal antibody.The B-cell maturation protein (BCMA or BCM) is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation. [provided by RefSeq, Jul 2008] |
| Product name | Anti-BCMA bispecific antibody (DM4) |
| Synonyms | TNFRSF17 |
| Type | Primary |
| Quantity | 100 µL |
| Shipping | Blue Ice |
| Antigen | BCMA |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone | DM4 |
| Isotype | Rabbit scfv |
| Application | Flow Cyt, MM Tumor cell killing |
| Immunogen substitute | Recombinant human BCMA (Met1-Ala54) (HDPT0001) produced by using human HEK293 cells |
| Purification | Purified from cell culture supernatant by affinity chromatography |
| Format | Liquid |
| Storage | Store at -20°C for 12 months (Avoid repeated freezing and thawing) |
| Usage | Research use only |
| Buffer | 50% Glycerol; PBS, pH 7.4; 0.1% BSA |
| Preservative | 0.1% Procline 300 |
| Reconstitution | Reconstitute with deionized water |
| Application Advice | Flow Cyt 1/100; MMTumor cell killing |
| Gene ID | 608 |
| Swiss-Prot | 608 |
| Molecular Weight | 20kDa |
| Assay Genie Related SKUs | HDPT0001 |
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