Anti-GITR antibody (DM79) Rabbit mAb (HDAB0066)
- SKU:
- HDAB0066
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Description
| Description | This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. |
| Product name | Anti-GITR antibody (DM79) Rabbit mAb |
| Synonyms | AITR, GITR, TNFRSF18, CD357 |
| Type | Primary |
| Quantity | 100 µL |
| Shipping | Blue Ice |
| Antigen | GITR |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone | DM79 |
| Isotype | Rabbit IgG |
| Application | ELISA,Flow Cyt |
| Immunogen substitute | Recombinant human GITR (Gln266-Pro162) (HDPT0018) produced by using human HEK293 cells |
| Purification | Purified from cell culture supernatant by affinity chromatography |
| Format | Liquid |
| Storage | Store at -20°C for 12 months (Avoid repeated freezing and thawing) |
| Usage | Research use only |
| Buffer | 50% Glycerol; PBS, pH 7.4; 0.1% BSA |
| Preservative | 0.1% Procline 300 |
| Reconstitution | Reconstitute with deionized water |
| Application Advice | ELISA 1/5000-10000;Flow Cyt 1/100 |
| Gene ID | 8784 |
| Swiss-Prot | Q9Y5U5 |
| Molecular Weight | 26.0kDa |
| Assay Genie Related SKUs | HDPT0018 |
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