CYP3A43 Polyclonal Antibody
- SKU:
- CAB8253
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Frequently bought together:
Description
| Product Name: | CYP3A43 Polyclonal Antibody |
| Product Code: | CAB8253 |
| Reactivity: | Human |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:2000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Cellular Location: | Endoplasmic reticulum membrane, Microsome membrane, Peripheral membrane protein |
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The encoded protein has a low level of testosterone hydroxylase activity, and may play a role in aging mechanisms and cancer progression. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Alternate splicing results in multiple transcript variants encoding different isoforms.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 134-393 of human CYP3A43 (NP_001265850.1). |
| Sequence: | DVTHF LKNSI ERMKE SRLKD KQKHR VDFFQ QMIDS QNSKE TKSHK ALSDL ELVAQ SIIII FAAYD TTSTT LPFIM YELAT HPDVQ QKLQE EIDAV LPNKA PVTYD ALVQM EYLDM VVNET LRLFP VVSRV TRVCK KDIEI NGVFI PKGLA VMVPI YALHH DPKYW TEPEK FCPER FSKKN KDSID LYRYI PFGAG PRNCI GMRFA LTNIK LAVIR ALQNF SFKPC KETQI PLKLD NLPIL QPEKP IVLKV HLRDG ITSGP |
| Synonyms: | CYP3A43 |
| Calculated MW: | 58kDa |
| Observed MW: | Refer to figures |