Anti-MOAP1 Antibody (CAB12599)

Antibody Name:	Anti-MOAP1 Antibody
Antibody SKU:	CAB12599
Antibody Size:	20uL, 50uL, 100uL
Application:	IHC
Reactivity:	Mouse, Rat
Host Species:	Rabbit
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-351 of human MOAP1 (NP_071434.2).

Application:	IHC
Recommended Dilution:	IHC 1:50 - 1:100
Reactivity:	Mouse, Rat
Positive Samples:

Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-351 of human MOAP1 (NP_071434.2).
Purification Method:	Affinity purification
Storage Buffer:	Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:	IgG
Sequence:	MTLR LLED WCRG MDMN PRKA LLIA GISQ SCSV AEIE EALQ AGLA PLGE YRLL GRMF RRDE NRKV ALVG LTAE TSHA LVPK EIPG KGGI WRVI FKPP DPDN TFLS RLNE FLAG EGMT VGEL SRAL GHEN GSLD PEQG MIPE MWAP MLAQ ALEA LQPA LQCL KYKK LRVF SGRE SPEP GEEE FGRW MFHT TQMI KAWQ VPDV EKRR RLLE SLRG PALD VIRV LKIN NPLI TVDE CLQA LEEV FGVT DNPR ELQV KYLT TYQK DEEK LSAY VLRL EPLL QKLV QRGA IERD AVNQ ARLD QVIA GAVH KTIR RELN LPED GPAP GFLQ LLVL IKDY EAAE EEEA LLQA ILEG NFT
Gene ID:	64112
Uniprot:	Q96BY2
Cellular Location:
Calculated MW:	39kDa
Observed MW:

Synonyms:	MOAP1, MAP-1, PNMA4
Background:	The protein encoded by this gene was identified by its interaction with apoptosis regulator BAX protein. This protein contains a Bcl-2 homology 3 (BH3)-like motif, which is required for the association with BAX. When overexpressed, this gene has been shown to mediate caspase-dependent apoptosis.

UniProt Protein Function:	MOAP1: Required for death receptor-dependent apoptosis. When associated with RASSF1, promotes BAX conformational change and translocation to mitochondrial membranes in response to TNF and TNFSF10 stimulation. Belongs to the PNMA family.
UniProt Protein Details:	Chromosomal Location of Human Ortholog: 14q32 Cellular Component: mitochondrial outer membrane; mitochondrion; cytoplasm; cytosol Molecular Function:protein binding; ubiquitin protein ligase binding Biological Process: DNA damage response, signal transduction resulting in induction of apoptosis; induction of apoptosis via death domain receptors; protein insertion into mitochondrial membrane during induction of apoptosis; positive regulation of apoptosis
NCBI Summary:	The protein encoded by this gene was identified by its interaction with apoptosis regulator BAX protein. This protein contains a Bcl-2 homology 3 (BH3)-like motif, which is required for the association with BAX. When overexpressed, this gene has been shown to mediate caspase-dependent apoptosis. [provided by RefSeq, Jul 2008]
UniProt Code:	Q96BY2
NCBI GenInfo Identifier:	19923584
NCBI Gene ID:	64112
NCBI Accession:	NP_071434.2
UniProt Secondary Accession:	Q96BY2,Q9H833, Q9HAS1, B2RDF6,
UniProt Related Accession:	Q96BY2
Molecular Weight:	39,513 Da
NCBI Full Name:	modulator of apoptosis 1
NCBI Synonym Full Names:	modulator of apoptosis 1
NCBI Official Symbol:	MOAP1
NCBI Official Synonym Symbols:	MAP-1; PNMA4
NCBI Protein Information:	modulator of apoptosis 1; MAP1; paraneoplastic Ma antigen family member 4; paraneoplastic antigen Ma4; paraneoplastic antigen like 4
UniProt Protein Name:	Modulator of apoptosis 1
UniProt Synonym Protein Names:	Paraneoplastic antigen Ma4
Protein Family:	Modulator of apoptosis
UniProt Gene Name:	MOAP1
UniProt Entry Name:	MOAP1_HUMAN

	Immunohistochemistry of paraffin-embedded rat kidney using MOAP1 antibody (CAB12599) at dilution of 1:100 (40x lens).
	Immunohistochemistry of paraffin-embedded rat heart using MOAP1 antibody (CAB12599) at dilution of 1:100 (40x lens).
	Immunohistochemistry of paraffin-embedded mouse brain using MOAP1 antibody (CAB12599) at dilution of 1:100 (40x lens).

Antibodies

Anti-MOAP1 Antibody (CAB5759)

Secondary Antibody

Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)