Anti-ANKRD2 Antibody (CAB4622)
- SKU:
- CAB4622
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- ANKRD2
- ARPP
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Product Name: | ANKRD2 Rabbit pAb |
| Product Code: | CAB4622 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | ANKRD2, ARPP |
| Applications: | WB |
| Reactivity: | Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 30-140 of human ANKRD2 (NP_001123453.1). |
| Applications: | WB |
| Recommended Dilutions: | WB 1:1000 - 1:2000 |
| Reactivity: | Mouse, Rat |
| Positive Samples: | Mouse skeletal muscle, Rat skeletal muscle |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 30-140 of human ANKRD2 (NP_001123453.1). |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | GTME DSEA VQRA TALI EQRL AQEE ENEK LRGD ARQK LPMD LLVL EDEK HHGA QSAA LQKV KGQE RVRK TSLD LRRE IIDV GGIQ NLIE LRKK RKQK KRDA LAAS HEPP PEP |
| Gene ID: | 26287 |
| Uniprot: | Q9GZV1 |
| Cellular Location: | Cytoplasm, I band, Nucleus, PML body, cytosol, myofibril, sarcomere |
| Calculated MW: | 36kDa/39kDa |
| Observed MW: | 42kDa |
| UniProt Protein Function: | ANKRD2: May play an important role in skeletal muscle hypertrophy. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Contractile Chromosomal Location of Human Ortholog: 10q23 Cellular Component: I band; PML body; euchromatin; sarcomere; intracellular membrane-bound organelle; nucleus; cytosol Molecular Function:protein kinase B binding; structural constituent of muscle; titin binding Biological Process: muscle development; muscle contraction; negative regulation of transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter in response to oxidative stress; negative regulation of myoblast differentiation |
| NCBI Summary: | This gene encodes a protein that belongs to the muscle ankyrin repeat protein (MARP) family. A similar gene in rodents is a component of a muscle stress response pathway and plays a role in the stretch-response associated with slow muscle function. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2014] |
| UniProt Code: | Q9GZV1 |
| NCBI GenInfo Identifier: | 182676433 |
| NCBI Gene ID: | 26287 |
| NCBI Accession: | Q9GZV1.3 |
| UniProt Secondary Accession: | Q9GZV1,Q3B778, Q5T456, Q70EZ9, Q8WUD7, Q96MG0, Q9NQC9 |
| UniProt Related Accession: | Q9GZV1 |
| Molecular Weight: | 36,193 Da |
| NCBI Full Name: | Ankyrin repeat domain-containing protein 2 |
| NCBI Synonym Full Names: | ankyrin repeat domain 2 (stretch responsive muscle) |
| NCBI Official Symbol: | ANKRD2Â Â |
| NCBI Official Synonym Symbols: | ARPPÂ Â |
| NCBI Protein Information: | ankyrin repeat domain-containing protein 2; skeletal muscle ankyrin repeat protein |
| UniProt Protein Name: | Ankyrin repeat domain-containing protein 2 |
| UniProt Synonym Protein Names: | Skeletal muscle ankyrin repeat protein; hArpp |
| Protein Family: | Ankyrin repeat domain-containing protein |
| UniProt Gene Name: | ANKRD2Â Â |
| UniProt Entry Name: | ANKR2_HUMAN |
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