Anti-CD27 antibody (DM59) Rabbit mAb (HDAB0049)

SKU:
HDAB0049
€630

Description

DescriptionThe protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.
Product nameAnti-CD27 antibody (DM59) Rabbit mAb
SynonymsCD27, TNFRSF7, S152, T14, Tp55
TypePrimary
Quantity100 µL
ShippingBlue Ice
AntigenCD27
ReactivityHuman
HostRabbit
ClonalityMonoclonal
CloneDM59
IsotypeRabbit IgG
ApplicationELISA,Flow Cyt
Immunogen substituteRecombinant human CD27 (Ala20-Arg191) (HDPT0087) produced by using human HEK293 cells
PurificationPurified from cell culture supernatant by affinity chromatography
FormatLiquid
StorageStore at -20°C for 12 months (Avoid repeated freezing and thawing)
UsageResearch use only
Buffer50% Glycerol; PBS, pH 7.4; 0.1% BSA
Preservative0.1% Procline 300
ReconstitutionReconstitute with deionized water
Application AdviceELISA 1/5000-10000;Flow Cyt  1/100
Gene ID939
Swiss-ProtP26842
Molecular Weight29 kDa
Assay Genie Related SKUsHDPT0087
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