Anti-CD47 antibody (DM49) Rabbit mAb (HDAB0039)

SKU:
HDAB0039
€630

Description

DescriptionLeukocyte surface antigen CD47 is also known as Antigenic surface determinant protein OA3, Integrin-associated protein (IAP) and Protein MER6. CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain. CD47 is very broadly distributed on normal adult tissues. CD47 has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins and plays an important role in memory formation and synaptic plasticity in the hippocampus by similarity. CD47 is the receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. CD47 Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation.
Product nameAnti-CD47 antibody (DM49) Rabbit mAb
SynonymsCD47, MER6, IAP, OA3
TypePrimary
Quantity100 µL
ShippingBlue Ice
AntigenCD47
ReactivityHuman
HostRabbit
ClonalityMonoclonal
CloneDM49
IsotypeRabbit IgG
ApplicationELISA,Flow Cyt
Immunogen substituteRecombinant human  CD47(Gln19-Glu141,Val198-Ala207,Ser257-Gly268) (HDPT0008) produced by using human HEK293 cells
PurificationPurified from cell culture supernatant by affinity chromatography
FormatLiquid
StorageStore at -20°C for 12 months (Avoid repeated freezing and thawing)
UsageResearch use only
Buffer50% Glycerol; PBS, pH 7.4; 0.1% BSA
Preservative0.1% Procline 300
ReconstitutionReconstitute with deionized water
Application AdviceELISA 1/5000-10000;Flow Cyt  1/100
Gene ID961
Swiss-ProtQ08722
Molecular Weight35 kDa
Assay Genie Related SKUsHDPT0008
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