Anti-mesothelin antibody (DM71) Rabbit mAb (HDAB0058)

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Description

Description	This gene encodes a preproprotein that is proteolytically processed to generate two protein products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
Product name	Anti-mesothelin antibody (DM71) Rabbit mAb
Synonyms	MSLN, Mesothelin, MPF
Type	Primary
Quantity	100 µL
Shipping	Blue Ice
Antigen	mesothelin
Reactivity	Human
Host	Rabbit
Clonality	Monoclonal
Clone	DM71
Isotype	Rabbit IgG
Application	ELISA,Flow Cyt
Immunogen substitute	Recombinant human mesothelin (Glu296-Gly580) (HDPT0031) produced by using human HEK293 cells
Purification	Purified from cell culture supernatant by affinity chromatography
Format	Liquid
Storage	Store at -20°C for 12 months (Avoid repeated freezing and thawing)
Usage	Research use only
Buffer	50% Glycerol; PBS, pH 7.4; 0.1% BSA
Preservative	0.1% Procline 300
Reconstitution	Reconstitute with deionized water
Application Advice	ELISA 1/5000-10000;Flow Cyt 1/100
Gene ID	10232
Swiss-Prot	Q13421
Molecular Weight	68.9kDa
Assay Genie Related SKUs	HDPT0031