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Anti-CXCL3 Antibody (CAB14226)

SKU:
CAB14226
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
CXCL3
CINC-2b
GRO3
GROg
MIP-2b
MIP2B
SCYB3
€129 - €359
Frequently bought together:

Description

Product Name:CXCL3 Rabbit pAb
Product Code:CAB14226
Size:20uL, 50uL, 100uL
Synonyms:CXCL3, CINC-2b, GRO3, GROg, MIP-2b, MIP2B, SCYB3
Applications:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-107 of human CXCL3 (NP_002081.2).
Applications:WB
Recommended Dilutions:WB 1:500 - 1:2000
Reactivity:Human
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-107 of human CXCL3 (NP_002081.2).
Purification Method:Affinity purification
Storage:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MAHA TLSA APSN PRLL RVAL LLLL LVAA SRRA AGAS VVTE LRCQ CLQT LQGI HLKN IQSV NVRS PGPH CAQT EVIA TLKN GKKA CLNP ASPM VQKI IEKI LNKG STN
Gene ID:2921
Uniprot:P19876
Cellular Location:Secreted
Calculated MW:11kDa
Observed MW:Refer to Figures
UniProt Protein Function:CXCL3: Ligand for CXCR2. Has chemotactic activity for neutrophils. May play a role in inflammation and exert its effects on endothelial cells in an autocrine fashion. In vitro, the processed form GRO-gamma(5-73) shows a fivefold higher chemotactic activity for neutrophilic granulocytes. Belongs to the intercrine alpha (chemokine CxC) family.
UniProt Protein Details:

Protein type:Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 4q21

Cellular Component: extracellular space; extracellular region

Molecular Function:chemokine activity; CXCR chemokine receptor binding

Biological Process: G-protein coupled receptor protein signaling pathway; neutrophil chemotaxis; response to lipopolysaccharide; positive regulation of leukocyte chemotaxis; immune response; inflammatory response; regulation of cell proliferation

NCBI Summary:This antimicrobial gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signals through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. [provided by RefSeq, Sep 2014]
UniProt Code:P19876
NCBI GenInfo Identifier:127086
NCBI Gene ID:2921
NCBI Accession:P19876.1
UniProt Secondary Accession:P19876,Q4W5H9,
UniProt Related Accession:P19876
Molecular Weight:11,342 Da
NCBI Full Name:C-X-C motif chemokine 3
NCBI Synonym Full Names:chemokine (C-X-C motif) ligand 3
NCBI Official Symbol:CXCL3  
NCBI Official Synonym Symbols:GRO3; GROg; MIP2B; SCYB3; MIP-2b; CINC-2b  
NCBI Protein Information:C-X-C motif chemokine 3; GRO-gamma; MIP2-beta; MGSA gamma; GRO3 oncogene; GRO-gamma(1-73); growth-regulated protein gamma; macrophage inflammatory protein 2-beta; melanoma growth stimulatory activity gamma
UniProt Protein Name:C-X-C motif chemokine 3
UniProt Synonym Protein Names:GRO-gamma(1-73); Growth-regulated protein gamma; GRO-gamma; Macrophage inflammatory protein 2-beta; MIP2-beta
UniProt Gene Name:CXCL3  
UniProt Entry Name:CXCL3_HUMAN

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