IL17A Polyclonal Antibody
- SKU:
- AGEL2132
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Rat
- Mouse
- Applications:
- FC
Frequently bought together:
Description
Overview:
| Title: | IL17A Polyclonal Antibody |
| Reactivity: | Human, Rat, Mouse |
| Application: | IHC |
| Dilution: | IHC 1:50-1:200 |
| Host: | Rabbit |
Background:
The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.
Product Information:
| Isotype: | IgG |
| Concentration: | 1mg/mL |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Purification Method: | Affinity purification |
| Research Areas: | Cancer, Immunology |
| Conjugation: | Unconjugated |
Immunogen Details:
| Immunogen: | Recombinant fusion protein of human IL17A. |
| Abbre: | IL17A |
| Synonyms: | IL17A,CTLA-8,CTLA8,IL-17,IL-17A,IL17. |
| Swissprot: | Q16552 |
| Gene ID: | 3605 |
| Cellular Localization: | Secreted |
| Tissue Specificity: | Restricted to activated memory T-cells. |
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