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Anti-IL-1F10 Antibody (CAB13133)

SKU:
CAB13133
Product Type:
Antibody
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Immunology
€139 - €419
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Description

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Antibody Name:IL1F10 Rabbit Polyclonal Antibody
Antibody SKU:CAB13133
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-152 of human IL1F10 (NP_115945.4).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Mouse
Positive Samples:Mouse kidney, Mouse heart
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-152 of human IL1F10 (NP_115945.4).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MCSL PMAR YYII KYAD QKAL YTRD GQLL VGDP VADN CCAE KICI LPNR GLAR TKVP IFLG IQGG SRCL ACVE TEEG PSLQ LEDV NIEE LYKG GEEA TRFT FFQS SSGS AFRL EAAA WPGW FLCG PAEP QQPV QLTK ESEP SART KFYF EQSW
Gene ID:84639
Uniprot:Q8WWZ1
Cellular Location:Secreted
Calculated MW:16kDa
Observed MW:17kDa
Synonyms:IL1F10, FIL1-theta, FKSG75, IL-1HY2, IL-38, IL1-theta, IL1HY2
Background:The protein encoded by this gene is a member of the interleukin 1 cytokine family. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. This cytokine is thought to participate in a network of interleukin 1 family members to regulate adapted and innate immune responses. Two alternatively spliced transcript variants encoding the same protein have been reported.
UniProt Protein Function:IL1F10: Binds soluble IL-1 receptor type 1. Belongs to the IL-1 family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Cytokine

Chromosomal Location of Human Ortholog: 2q13

Cellular Component: extracellular space

Molecular Function:interleukin-1 receptor binding; cytokine activity

Biological Process: cytokine and chemokine mediated signaling pathway

NCBI Summary:The protein encoded by this gene is a member of the interleukin 1 cytokine family. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. This cytokine is thought to participate in a network of interleukin 1 family members to regulate adapted and innate immune responses. Two alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq, Jul 2008]
UniProt Code:Q8WWZ1
NCBI GenInfo Identifier:25008589
NCBI Gene ID:84639
NCBI Accession:Q8WWZ1.1
UniProt Secondary Accession:Q8WWZ1,Q53SR9, Q56AT8, Q7RTZ5, Q969H5, Q9BYX1,
UniProt Related Accession:Q8WWZ1
Molecular Weight:16,943 Da
NCBI Full Name:Interleukin-1 family member 10
NCBI Synonym Full Names:interleukin 1 family, member 10 (theta)
NCBI Official Symbol:IL1F10  
NCBI Official Synonym Symbols:IL-38; FKSG75; IL1HY2; IL-1HY2; IL1-theta; FIL1-theta  
NCBI Protein Information:interleukin-1 family member 10; FIL1 theta; IL-1 theta; interleukin-38; interleukin-1 HY2; family of interleukin 1-theta; IL-1F10 (canonical form IL-1F10a); interleukin-1 receptor antagonist FKSG75; interleukin-1 receptor antagonist-like FIL1 theta
UniProt Protein Name:Interleukin-1 family member 10
UniProt Synonym Protein Names:Family of interleukin 1-theta; FIL1 theta; Interleukin-1 HY2; IL-1HY2; Interleukin-1 theta; IL-1 theta; Interleukin-38
UniProt Gene Name:IL1F10  
UniProt Entry Name:IL1FA_HUMAN
Anti-IL-1F10 Antibody (CAB13133)Western blot analysis of extracts of various cell lines, using IL1F10 antibody (CAB13133) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.

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