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Anti-IRF2BP1 Antibody (CAB4614)

SKU:
CAB4614
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Mouse
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
IRF2BP1
Research Area:
Epigenetics and Nuclear Signaling
  • Epigenetics and Nuclear Signaling Antibodies 3 Anti-IRF2BP1 Antibody CAB4614
  • Epigenetics and Nuclear Signaling Antibodies 3 Anti-IRF2BP1 Antibody CAB4614
€139 - €419
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Description

Product Name:IRF2BP1 Rabbit pAb
Product Code:CAB4614
Size:20uL, 50uL, 100uL
Synonyms:IRF2BP1
Applications:WB
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 60-240 of human IRF2BP1 (NP_056464.1).
Applications:WB
Recommended Dilutions:WB 1:500 - 1:2000
Reactivity:Human, Mouse
Positive Samples:U-87MG, HeLa, Jurkat, Mouse eye
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 60-240 of human IRF2BP1 (NP_056464.1).
Purification Method:Affinity purification
Storage:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:VLPE GRSP GPPA LKHP ATKD LAAA AAQG PQLP PPQA QPQP SGTG GGVS GQDR YDRA TSSG RLPL PSPA LEYT LGSR LANG LGRE EAVA EGAR RALL GSMP GLMP PGLL AAAV SGLG SRGL TLAP GLSP ARPL FGSD FEKE KQQR NADC LAEL NEAM RGRA EEWH GRPK AVRE QLLA LSAC A
Gene ID:26145
Uniprot:Q8IU81
Cellular Location:Nucleus
Calculated MW:61kDa
Observed MW:62kDa
UniProt Protein Function:IRF2BP1: Acts as a transcriptional corepressor in a IRF2- dependent manner; this repression is not mediated by histone deacetylase activities. May act as an E3 ligase towards JDP2, enhancing its polyubiquitination. Represses ATF2-dependent transcriptional activation. Belongs to the IRF2BP family.
UniProt Protein Details:

Protein type:Transcription, coactivator/corepressor; EC 6.3.2.-

Chromosomal Location of Human Ortholog: 19q13.32

Cellular Component: nucleoplasm; intracellular membrane-bound organelle

Molecular Function:protein binding; metal ion binding; ligase activity

Biological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent

UniProt Code:Q8IU81
NCBI GenInfo Identifier:74727955
NCBI Gene ID:26145
NCBI Accession:Q8IU81.1
UniProt Secondary Accession:Q8IU81,Q53EL7, Q6DC95, Q9BRZ9, Q9Y4P4,
UniProt Related Accession:Q8IU81
Molecular Weight:584
NCBI Full Name:Interferon regulatory factor 2-binding protein 1
NCBI Synonym Full Names:interferon regulatory factor 2 binding protein 1
NCBI Official Symbol:IRF2BP1  
NCBI Protein Information:interferon regulatory factor 2-binding protein 1; IRF-2-binding protein 1; probable E3 ubiquitin-protein ligase IRF2BP1
UniProt Protein Name:Interferon regulatory factor 2-binding protein 1
UniProt Synonym Protein Names:Probable E3 ubiquitin-protein ligase IRF2BP1 (EC:6.3.2.-)
Protein Family:Interferon regulatory factor 2-binding protein
UniProt Gene Name:IRF2BP1  
UniProt Entry Name:I2BP1_HUMAN

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