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Anti-MT3 Antibody (CAB20541)

SKU:
CAB20541
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
GIF
GIFB
GRIF
ZnMT3
€259 - €359
Frequently bought together:

Description

Product Name:MT3 Rabbit pAb
Product Code:CAB20541
Size:50uL, 100uL
Synonyms:GIF, GIFB, GRIF, ZnMT3
Applications:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:Recombinant protein of human MT3.
Applications:WB
Recommended Dilutions:WB 1:500 - 1:2000
Reactivity:Human
Immunogen:Recombinant protein of human MT3.
Purification Method:Affinity purification
Storage:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:4504
Uniprot:P25713
Calculated MW:6kDa
Observed MW:Refer to figures
UniProt Protein Function:MT3: Binds heavy metals. Contains three zinc and three copper atoms per polypeptide chain and only a negligible amount of cadmium. Inhibits survival and neurite formation of cortical neurons in vitro. Belongs to the metallothionein superfamily. Type 1 family.
UniProt Protein Details:

Chromosomal Location of Human Ortholog: 16q13

Cellular Component: synaptic vesicle; perinuclear region of cytoplasm; cytoplasm; inclusion body; intracellular

Molecular Function:antioxidant activity; protein binding; copper ion binding; zinc ion binding; caspase inhibitor activity; drug binding; cadmium ion binding; protein kinase activator activity

Biological Process: positive regulation of catalytic activity; negative regulation of autophagy; removal of superoxide radicals; positive regulation of transcription, DNA-dependent; negative regulation of axon extension; negative regulation of caspase activity; positive regulation of vascular endothelial growth factor receptor signaling pathway; zinc ion homeostasis; cadmium ion homeostasis; cellular lipid catabolic process; histone modification; protein kinase B signaling cascade; negative regulation of neuron apoptosis; cholesterol catabolic process; regulation of response to food; protein stabilization; cellular zinc ion homeostasis; activation of protein kinase B; zinc ion transport; regulation of protein amino acid glycosylation; astrocyte development; leptin-mediated signaling pathway; cell proliferation; cellular metal ion homeostasis; protein import into nucleus, translocation; negative regulation of oxidoreductase activity; response to hypoxia; energy reserve metabolic process; positive regulation of protein amino acid phosphorylation; negative regulation of cell growth; negative regulation of transcription, DNA-dependent; negative regulation of apoptosis

UniProt Code:P25713
NCBI GenInfo Identifier:5174762
NCBI Gene ID:4504
NCBI Accession:NP_005945.1
UniProt Secondary Accession:P25713,Q2V574,
UniProt Related Accession:P25713
Molecular Weight:6,927 Da
NCBI Full Name:metallothionein-3
NCBI Synonym Full Names:metallothionein 3
NCBI Official Symbol:MT3  
NCBI Official Synonym Symbols:GIF; GIFB; GRIF; ZnMT3  
NCBI Protein Information:metallothionein-3; MT-3; MT-III; metallothionein-III; growth inhibitory factor; metallothionein 3 (growth inhibitory factor (neurotrophic))
UniProt Protein Name:Metallothionein-3
UniProt Synonym Protein Names:GIFB; GIF; Growth inhibitory factor; Metallothionein-III
Protein Family:Metallothionein
UniProt Gene Name:MT3  
UniProt Entry Name:MT3_HUMAN

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