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Anti-NDUFV3 Antibody (CAB3986)

SKU:
CAB3986
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology
€139 - €419
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Description

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Antibody Name:Anti-NDUFV3 Antibody
Antibody SKU:CAB3986
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-108 of human NDUFV3 (NP_001001503.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human
Positive Samples:HepG2
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-108 of human NDUFV3 (NP_001001503.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MAAP CLLR QGRA GALK TMLQ EAQV FRGL ASTV SLSA ESGK SEKG QPQN SKKQ SPPK KPAP VPAE PFDN TTYK NLQH HDYS TYTF LDLN LELS KFRM PQPS SGRE SPRH
Gene ID:4731
Uniprot:P56181
Cellular Location:Matrix side, Mitochondrion inner membrane, Peripheral membrane protein
Calculated MW:11kDa/50kDa
Observed MW:10kDa
Synonyms:NDUFV3, CI-10k, CI-9KD
Background:The protein encoded by this gene is one of at least forty-one subunits that make up the NADH-ubiquinone oxidoreductase complex. This complex is part of the mitochondrial respiratory chain and serves to catalyze the rotenone-sensitive oxidation of NADH and the reduction of ubiquinone. The encoded protein is one of three proteins found in the flavoprotein fraction of the complex. The specific function of the encoded protein is unknown. Two transcript variants encoding different isoforms have been found for this gene.
UniProt Protein Function:NDUFV3: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Belongs to the complex I NDUFV3 subunit family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Mitochondrial; Oxidoreductase; Energy Metabolism - oxidative phosphorylation

Chromosomal Location of Human Ortholog: 21q22.3

Cellular Component: mitochondrial inner membrane; mitochondrial respiratory chain complex I; mitochondrion; nucleoplasm

Biological Process: mitochondrial electron transport, NADH to ubiquinone; mitochondrial respiratory chain complex I assembly

NCBI Summary:The protein encoded by this gene is one of at least forty-one subunits that make up the NADH-ubiquinone oxidoreductase complex. This complex is part of the mitochondrial respiratory chain and serves to catalyze the rotenone-sensitive oxidation of NADH and the reduction of ubiquinone. The encoded protein is one of three proteins found in the flavoprotein fraction of the complex. The specific function of the encoded protein is unknown. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Code:P56181
NCBI GenInfo Identifier:20178326
NCBI Gene ID:4731
NCBI Accession:P56181.2
UniProt Secondary Accession:P56181,Q6FGD3, Q8WU60, Q9HCR5, A8K0M1, J3KNX7,
UniProt Related Accession:P56181
Molecular Weight:50,984 Da
NCBI Full Name:NADH dehydrogenase
NCBI Synonym Full Names:NADH:ubiquinone oxidoreductase subunit V3
NCBI Official Symbol:NDUFV3  
NCBI Official Synonym Symbols:CI-10k; CI-9KD  
NCBI Protein Information:NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial
UniProt Protein Name:NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial
UniProt Synonym Protein Names:Complex I-9kD; CI-9kD; NADH-ubiquinone oxidoreductase 9 kDa subunit; Renal carcinoma antigen NY-REN-4
Protein Family:NADH dehydrogenase [ubiquinone] flavoprotein
UniProt Gene Name:NDUFV3  
UniProt Entry Name:NDUV3_HUMAN
Anti-NDUFV3 Antibody (CAB3986)Western blot analysis of extracts of HepG2 cells, using NDUFV3 antibody (CAB3986). Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST.

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